Missing Players and team news:
Reims will welcome teenage protege Nathanael Mbuku back from suspension for this tie, but midfielder Moreto Cassama will serve a ban of his own for an accumulation of bookings. Marshall Munetsi is therefore set for a swift recall to the engine room for Guion’s side, while Arber Zeneli was one of three half-time substitutions made by Guion against Nantes and could find his spot on the left under threat from the returning Dia. Xavier Chavalerin was forced off last time out due to a cut on his knee, but Guion expects him to be fine for this encounter after he was stitched up, meaning that Reims have an empty medical room at this moment in time. Lyon are also blessed with an unoccupied treatment room, and the visitors will welcome a player of their own back from suspension in Lucas Paqueta, who played 90 minutes in the cup and should reprise his role on Friday too. Teenage protege Rayan Cherki bagged a brace against Sochaux but is expected to drop out for the returning Karl Toko Ekambi here, while Depay and Thiago Mendes are also in line to replace Islam Slimani and Bruno Guimaraes. Garcia handed opportunities to several fringe defenders in the Coupe de France, but the quartet of Anthony Lopes, Jason Denayer, Marcelo and Leo Dubois will all come back on Friday, while Tino Kadewere has successfully shaken off a muscular problem.