KICK off: 2 February 22:15
Information: United will again be without the services of out-of-favour pair Phil Jones and Marcos Rojo, and there is a strong chance that the latter could have left the club before Tuesday’s contest. Scott McTominay is also a doubt, with the Scotland international being forced off against Arsenal due to stomach cramp, and it remains to be seen whether the midfielder recovers from the illness in time. Solskjaer is expected to make changes to his starting XI, with Nemanja Matic and Eric Bailly in line for starts, while Anthony Martial could also return to the centre-forward position. Martial has only scored two Premier League goals this season, but Cavani again played the full 90 minutes against Arsenal on Saturday and could be rested amid a busy run of matches. As for Southampton, Mohammed Salisu, Nathan Tella, Michael Obafemi and William Smallbone are still injured, while the match is also expected to come too soon for Jannik Vestergaard and Kyle Walker-Peters. Head coach Hasenhuttl is likely to stick with the majority of the side that started Saturday’s loss to Villa, with Oriol Romeu expected to shake off an injury complaint to feature. There could be a change in the final third, though, with Che Adams coming in alongside Danny Ings, while there might also be an alteration at right-back with Yan Valery potentially starting. Theo Walcott is a major doubt with the problem that he picked up against Villa, meaning that Nathan Redmond, who played through the middle last time out, could earn a start in a wide position.
Prediction: Over 2,5 goals
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Prediction of the day: Manchester United – Southampton