Napoli’s list of absences stubbornly refuses to reduce in size, to the frustration of coach Gennaro Gattuso. His first-choice central defensive pairing of Kostas Manolas (injured) and Kalidou Koulibaly (suspended) will be missing again, so the rather less resilient duo of Nikola Maksimovic and Amir Rrahmani are set to fill in. In attack, Victor Osimhen – who is currently suffering from a head injury, having previously been sidelined by a shoulder strain and then COVID-19 – Hirving Lozano and Andrea Petagna all remain unavailable. Following his 250th Serie A appearance at the weekend – celebrated with yet another goal – Dries Mertens should start again up front, with Matteo Politano and Lorenzo Insigne in support. Sassuolo have few injury concerns ahead of the game, with only winger Jeremie Boga and midfielder Mehdi Bourabia set to miss out, as former Napoli man Vlad Chiriches could contend for a role in the back four, having returned to full fitness. Francesco Caputo will be at the apex of Roberto De Zerbi’s customary 4-2-3-1 formation, with Domenico Berardi in close support, but several contenders remain for two further slots – including Gregoire Defrel, Hamed Traore, Filip Djuricic and Lukas Haraslin.
Missing Players and team news: