Missing Players and team news:

Arteta will prioritise next Thursday’s return fixture with Slavia over this trip to Bramall Lane, which could mean returns for the likes of Mohamed Elneny and Calum Chambers. Pierre-Emerick Aubameyang was dropped for the first-leg draw against the Czech champions, but he assisted Pepe’s goal from the bench and seems likely to be involved here. Martin Odegaard was not included in the squad last time out because of an ankle injury, and Arteta is not confident of the midfielder returning this weekend. Influential full-back Kieran Tierney and experienced centre-back David Luiz are the Gunners’ other two injury absentees. As for the home team, they will not be allowed to call upon Jayden Bogle and George Baldock after the pair were taken off with concussion against Leeds. That leaves the Blades seriously short of defensive options on the right. Enda Stevens could fill in there, which in turn would mean a return to the XI for Ethan Ampadu. Oli McBurnie and David McGoldrick are Heckingbottom’s go-to choice up top, but Lys Mousset and Rhian Brewster are among those pushing for inclusion.